Chinook Therapeutics is a clinical-stage biotechnology company developing precision medicines for kidney diseases. Chinook’s product candidates are being investigated in rare, severe chronic kidney disorders with opportunities for well-defined clinical pathways. Chinook’s lead program is atrasentan, a phase 3 endothelin receptor antagonist for the treatment of IgA nephropathy and other proteinuric glomerular diseases. BION-1301, an anti-APRIL monoclonal antibody is being evaluated in a phase 1/2 trial for IgA nephropathy. In addition, Chinook is advancing CHK-336, an oral small molecule LDHA inhibitor for the treatment of primary hyperoxaluria, as well as research programs for other rare, severe chronic kidney diseases.
Chinook is building its pipeline by leveraging insights in kidney single cell RNA sequencing, human-derived organoids, and new translational models, to discover and develop therapeutics with differentiating mechanisms of action against key kidney disease pathways. Chinook trades on Nasdaq under the ticker symbol KDNY and has locations in Vancouver, BC, Seattle, WA and Oakland, CA.
The Director/Senior Director, Biologics Process Development (PD) will provide first-class scientific and managerial leadership in support of Chinook’s BION-1301 program through clinical development, commercial launch, and life cycle management.
As a technical leader in a medium-sized company relying on a fully outsourced supply chain, the Director/Senior Director, Biologics PD will act as a subject matter expert (SME) in drug substance (DS) process and formulation development, technology transfer, and cGMP manufacturing oversight at Chinook’s contracted vendors. She/he will work closely with other functional areas in Technical Operations and Quality to ensure timely manufacture of high-quality drug substances to support Chinook’s biologics programs. She/he will also work with Technical Operations leadership in defining biologics development and manufacturing strategies and build the biologics PD team accordingly.
This position is remote and reports to the Executive Director, Biologics Development and Manufacturing.
Education, Experience, and Skills:
Chinook is an Equal Opportunity Employer, and we prohibit discrimination or harassment of any kind. We are committed to fostering an environment where ALL people are welcome and supported. We respect and value different experiences and viewpoints. We act respectfully toward one another and embrace diversity of people and ideas. Having a diverse workforce made up of team members who bring a wide variety of skills, abilities, experiences, and perspectives is essential to our success. Creativity and innovation flourish in an environment of openness, inclusion, and mutual respect
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